BSc thesis
September 2026
Excellent · 10/10
Inverse problems · PyTorch · Medical imaging
When a generative prior
helps—and when it fails.
Score-based reconstruction of undersampled MRI, from faithful reproduction to uncertainty and domain shift.
I reimplemented a published MRI reconstruction solver in PyTorch, converted its pretrained JAX/Flax checkpoint, and studied reconstruction quality, sampling cost and the reliability of uncertainty estimates.
Thesis reports PSNR agreement with the reference on 256 BraTS
test slices, across 4×, 8× and 24× undersampling.
Thesis, Table 5.1
Methods, findings & limitations
What I implemented
The inverse-problem pipeline, measurement operators, conditioning and data consistency, four solver modes, checkpoint conversion and experiment analysis. The original model architecture and pretrained prior are credited to the reference work.
What the experiments showed
Sample averaging improved reconstruction at additional sampling cost. Short adaptation was evaluated under domain shift, including a subject-disjoint OASIS-1 study. Uncertainty-guided acquisition did not outperform random selection under an equal extra-column budget.
What this does not establish
These are retrospective, single-coil reconstruction experiments on public imaging datasets. Uncertainty ranking is not a calibrated probability of failure. There was no prospective scanner study or clinical validation.

